Characterization of AAV Genome Integrity Using 2D-ddPCR

Time: 1:00 pm
day: Track B - Day 1 PM


  • To characterize genome integrity, a duplex ddPCR method is developed to target the 5’-end and 3’-end of the AAV genome simultaneously which measures the percentage of full genome
  • 2D-ddPCR has been demonstrated to correlate with orthogonal methods in characterizing genome integrity