Quality attributes and extended characterization of gene vectors using light scattering

Time: 11:30 am
day: Track A - Day 1 AM

Details:

• Quantifying quality attributes of vectors is of increasing
importance as the gene therapy products enter into the
late development stages and QC environment.

• Batch dynamic light scattering (DLS) is for rapid screening,
size exclusion chromatography coupled to multi-angle
light scattering (SEC-MALS) for multiple AAV CQAs
quantification, and field-flow fractionation (FFF) with
MALS for quantifying AAV aggregates and extended
characterization of large gene vectors.

Speakers: