Company: Logic Bio
Job title: Associate Director, Analytical Development
Lauren M. Drouin leads the Analytical Development group at LogicBio Therapeutics, where she supports the development and implementation of analytical methodologies needed to progress LB-001 and other pipeline products from preclinical development into the clinic. Previously, Lauren worked at Voyager Therapeutics where she was responsible for both analytical method development and overseeing CMC analytics operations for the Phase II VY-AADC02 program. Lauren received her PhD in Biochemistry and Molecular Biology from the University of Florida where she utilized biophysical and structural techniques to characterize the AAV capsid for improved gene delivery.
Developing a Potency Assay for GeneRide Products: an AAV-based Genome Editing Platform 1:45 pm
The Gene Ride platform utilizes the natural process of homologous recombination to achieve targeted genome editing without the use of exogenous nucleases. Current guidance on potency assay development will be discussed, including specific obstacles for gene therapy products. Developing a potency assay for GeneRide vectors demonstrates additional challenges including low levels of integration which requires…Read more
day: Day One