Ronald Toth

Company: Sanofi

Job title: Associate Director, Characterization, Genomic Medicine Unit


Understanding Degradation Pathways to Develop Degradation Panels for Extended Characterization 3:00 pm

Data are presented demonstrating that genome ejection, and not aggregation, is the major degradation pathway for AAVs Routinely measuring free DNA and temperature of genome ejection is vital to understand this degradation pathway A starting point is given for developing a genome ejection assay that can be performed on any real-time PCR instrumentRead more

day: Conference Day Two

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