Zichuan Zhang

Zichuan Zhang

Company: Sanofi

Job title: Senior Scientist, Analytical Team Leader

Bio:

Dr. Zichuan (Zack) Zhang received his Ph.D. in Pharmaceutical Sciences from the University of Wisconsin Madison in 2013 and is currently a Senior Scientist at Sanofi Biologics Development. Prior to joining Sanofi Dr. Zhang worked for a contract research organization where he was involved in analytical method development, assay validation, commercial release and stability testing, as well as analytical CMC program management for a variety of therapeutic modalities. At Sanofi Dr. Zhang serves as an analytical program team lead and as a subject matter expert on electrophoretic separations. He is currently leading a group focused on the development and validation of CE-based separation methods for Adeno-associated virus based gene therapy products, monoclonal antibodies, and other therapeutic proteins. This includes exploring novel labeling approaches to enable CE-LIF detection of AAV capsid proteins for routine sample analysis in a GMP environment.

Seminars:

AAV Capsid Purity: the Control Strategy & the Evaluation of CE-SDS with LIF Detection 6:00 pm

Insights into the current strategies and gaps for determining capsid protein purity of AAV gene therapy candidates Providing an overview of novel labeling approaches to enable CE-LIF detection of AAV capsid proteins CE-LIF could be a QC-friendly method for routine monitoring of capsid purity compared with other CE-based analysisRead more

day: Day One

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