Pre-Conference Workshops
Morning Workshops
Workshop A: 6am-9am PST | 9am-12pm EST
A Deep Dive into Potency Assays
Navigating the challenges of developing clinically relevant potency assays for gene therapy products
Workshop Leader:
Marina Feschenko, Director - Analytical Development, Biogen
Hui-wen Liu, Scientist I , Biogen
Workshop B: 6am-9am PST | 9am-12pm EST
The Switch to Digital PCR
Discussing the challenges of switching from qPCR to digital PCR, whilst exploring the advantages and limitations of each technology
Workshop Leader:
Clare Blue, Director, Analytical Development, Biogen
David Dobnik, Scientific Associate, Head of Laboratory for Therapeutic Viruses, National Institute of Biology
Yu Wang, Senior Scientist, Analytical Development, Biogen
Workshop C: 6am-9am PST | 9am-12pm EST
The Effort for QC-Friendly Empty-Full & Partial Characterisation
Exploring the analytical technologies used for empty-full characterisation and how these can be incorporated into a suitable QC environment
Workshop Leader:
John Little, Director, Quality Control, Freeline Therapeutics
Afternoon Workshops
Workshop D: 10am-1pm PST | 1pm-4pm EST
Ex Vivo Gene Therapy Product Analytics
Discussing the specific analytical challenges for ex vivo
gene therapy products, from potency to characterization.
Workshop Leader:
Scott Burger, Principal, Advanced Cell & Gene Therapy, LLC
Workshop E: 10am-1pm PST | 1pm-4pm EST
High Throughput: Next Generation Sequencing Technology
Discovering the potential of characterization of AAV stocks by high-throughput sequencing: residual DNA, genome identity and integrity, sequencing biases
Workshop Leader:
Magalie Penaud-Budloo, Postdoctoral Research Scientist, Translational Gene Therapy for Genetic Diseases, INSERM
Workshop F: 10am-1pm PST | 1pm-4pm EST
Characterizing Aggregates
Developing orthogonal methods for rAAV vector aggregate characterization and exploring the advantages and disadvantages of DLS, SEC-HPLC, nsTEM and other methods
Workshop Leaders:
Franz Schnetzinger, Director, Quality Control & CMC Analytical Development, Gyroscope Therapeutics
Andrea Hamilton, QC Senior Scientist, Gyroscope Therapeutics